Our tripartite ecosystem brings together transnational (local, national, international), transdisciplinary (technology, art, science), and transmedia (digital media platforms) efforts. Through this collaborative framework, we co-create activations among researchers and practitioners in higher education across Colombia, Egypt, and Canada. As visual arts and science educators, our project experiments with the intersections of art, science, and technology. We prioritize pedagogical activations locally and globally, focusing on a ‘glocal’ approach that emphasizes learning points relevant to the 21st century. These learning points—or impact literacies—equip students with essential skills, including: Transnational partnerships, collaborative teamwork, responsiveness and adaptability, and innovative thinking. By incorporating these skills into the project design, we provide students with leadership opportunities that might not have been available otherwise.